JAMA Internal Medicine  2021.01.25

Cumulative exposure to cigarette smoke was associated with more severe outcomes among individuals testing positive for COVID-19, including higher risks of hospitalization and death, researchers found.

Compared with never smokers, those with smoking histories of more than 30 pack-years had 2.25 higher odds of hospitalization due to COVID-19 (95% CI 1.76-2.88), after adjustment for age, race, and sex, reported Katherine Lowe, MSc, of Cleveland Clinic Lerner College of Medicine of Case Western Reserve University School of Medicine.